{"id":15,"date":"2021-08-10T10:46:35","date_gmt":"2021-08-10T10:46:35","guid":{"rendered":"https:\/\/www.bsereview.org.uk\/?page_id=15"},"modified":"2021-08-10T10:46:35","modified_gmt":"2021-08-10T10:46:35","slug":"how-does-the-disease-progress","status":"publish","type":"page","link":"https:\/\/www.bsereview.org.uk\/how-does-the-disease-progress\/","title":{"rendered":"How does the disease progress?"},"content":{"rendered":"\n<p>As the disease progresses, more and more prion proteins are caused to deform into the beta pleated sheet, or infectious, state. As the deformed proteins increase in number, the degeneration process increases exponentially, and leads to the appearance of microscopic \u2018holes\u2019 in the brain. It is these holes which lead to the \u2018spongy\u2019 degeneration of the brain and spinal cord.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>As the disease progresses, more and more prion proteins are caused to deform into the beta pleated sheet, or infectious, state. As the deformed proteins increase in number, the degeneration process increases exponentially, and leads to the appearance of microscopic \u2018holes\u2019 in the brain. It is these holes which lead to the \u2018spongy\u2019 degeneration of the brain and spinal cord.<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bsereview.org.uk\/wp-json\/wp\/v2\/pages\/15"}],"collection":[{"href":"https:\/\/www.bsereview.org.uk\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bsereview.org.uk\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bsereview.org.uk\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bsereview.org.uk\/wp-json\/wp\/v2\/comments?post=15"}],"version-history":[{"count":1,"href":"https:\/\/www.bsereview.org.uk\/wp-json\/wp\/v2\/pages\/15\/revisions"}],"predecessor-version":[{"id":16,"href":"https:\/\/www.bsereview.org.uk\/wp-json\/wp\/v2\/pages\/15\/revisions\/16"}],"wp:attachment":[{"href":"https:\/\/www.bsereview.org.uk\/wp-json\/wp\/v2\/media?parent=15"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}